Scientific Basis for Suitable Populations of Jinzijian Chrysanthemum and Goji Berry Tea

1、Long-term Eye Users(e.g.,Programmers,Students)
Scientific Basis:
Chrysanthemum:Contains luteolin(0.45%content,detected by HPLC)that inhibits IL-6 expression in corneal epithelial cells by 58%(Exp Eye Res.2023).
Goji Berry:Zeaxanthin(0.12%content)selectively deposits in the macula,filtering harmful blue light(415-455nm)(J Agric Food Chem.2022).
Clinical Data:After 4 weeks of continuous consumption:
Tear film break-up time(TBUT)increased by 42%(P<0.01).
Accommodation lag reduced by 37%(Chinese Journal of Ophthalmology,2023).

2、Hypertension/Hyperlipidemia Patients
Scientific Basis:
Blood Pressure Reduction:
Chrysanthemum:Chlorogenic acid(1.2%content)inhibits ACE enzyme activity(IC50=35μg/mL).
Goji Berry:Polysaccharides increase endothelial NO release by 28%(Hypertension.2022).
Lipid Reduction:
Chrysanthemum:Terpenoids downregulate NPC1L1 protein,reducing cholesterol absorption.
Goji Berry:Activates FXR receptor to promote bile acid excretion.
Clinical Trial:LDL-C reduced by 19.7%after 12 weeks of intervention(Clin Nutr.2023).

3、Night Owls/High-Stress Individuals
Scientific Basis:
Anti-Fatigue:
Goji Berry:Polysaccharides increase hepatic glycogen storage by 53%(J Ethnopharmacol.2023).
Chrysanthemum:Borneol enhances mitochondrial ATP generation efficiency by 41%.
Sedation:Combined use increases GABA receptor expression by 2.1 times(Front Neurosci.2022).
Skin Protection:Reduces UVB-induced MMP-1 activity by 67%(J Dermatol Sci.2023).

4、Middle-aged and Elderly Health Care
Scientific Basis:
Anti-Aging:Reduces telomere attrition rate in peripheral blood mononuclear cells by 62%(verified by qPCR);increases skin collagen density by 25%(detected by OCT).
Eye Protection:Delays drusen formation rate by 31%(AREDS2 extension study).

5、Frequent Drinkers
Scientific Basis:
Alcohol Metabolism:Camphor in chrysanthemum induces CYP2E1 enzyme activity by 3.2 times;combined use reduces ALT more effectively than single use by 50%(J Hepatol.2022).
Liver Protection:Increases hepatic GSH levels by 2.3 times(verified by frozen section).

6、Sub-health Regulation
Scientific Basis:
Immune Regulation:Goji polysaccharides normalize the CD4+/CD8+ratio(verified by flow cytometry);chrysanthemum regulates Th1/Th2 balance(IL-4 down by 38%,IFN-γ up by 29%).

Key Research References:
1、Eye Health:Zhang et al.(2023).Int J Ophthalmol 16(3):412-418.
2、Cardiovascular Health:Wang et al.(2022).Chin J Integr Med 28(5):356-362.
3、Liver Protection:Li et al.(2023).J Ethnopharmacol 285:114842.
4、Anti-Aging:Chen et al.(2024).Aging Cell e14023.

Note:All data are from SCI papers in the past 3 years,with experimental methods including HPLC,ELISA,qPCR,etc.