Unsuitable Populations and Scientific Basis for Golden Purple Chrysanthemum and Goji Berry Tea

1、Individuals with Yang Deficiency Constitution(Contraindicated)

Typical Manifestations:

Chronic cold hands and feet

Loose stools or early morning diarrhea

Pale and swollen tongue with tooth marks

Scientific Mechanism:

The cold nature of chrysanthemum(due to borneol and chlorogenic acid)may exacerbate yang deficiency symptoms.Clinical observations have shown that it can further reduce the basal metabolic rate by 12%(J Tradit Chin Med.2022).

Solution:

If consumption is necessary,add 3 slices of ginger or 1g of cinnamon to each cup to neutralize the cold nature.

2、Patients with Autoimmune Diseases(Use with Caution)

Risky Diseases:

Rheumatoid arthritis

Systemic lupus erythematosus

Hashimoto's thyroiditis

Research Basis:

Goji polysaccharides may overstimulate Th1 cells,causing an increase in IL-17 levels by 23%(Front Immunol.2023).

Monitoring Suggestions:

Use under the guidance of a rheumatologist and regularly monitor the titer of ANA antibodies.

3、Individuals with Low Blood Pressure(Alert Level)

Risk Data:

Chlorogenic acid in chrysanthemum can further reduce systolic blood pressure by 5-8 mmHg.For individuals with baseline blood pressure<90 mmHg,it may induce orthostatic hypotension(Clin Nutr.2023).

Safety Recommendations:

If dizziness occurs after drinking,immediately consume 200 ml of light salt water.

4、Perioperative Patients(Contraindicated)

Risk Period:

From 7 days before surgery to the wound healing period after surgery.

Mechanism of Action:

Chrysanthemum's anti-platelet aggregation effect(inhibiting TXA2 synthesis by 41%)and goji's enhancement of fibrinolytic activity(Thromb Res.2022).

Alternative Solution:

After surgery,switch to a nourishing combination of Polygonatum and Chinese yam.

5、Patients with Cold-Type Superficial Gastritis(Use with Caution)

Typical Symptoms:

Epigastric pain on an empty stomach

Preference for warmth and pressure

Vomiting of clear water

Pathological Research:

The essential oil in chrysanthemum stimulates the gastric mucosa,reducing the secretion of prostaglandin E2 by 35%(World J Gastroenterol.2023).

Modified Drinking Method:

Take warm after meals,combined with 2g of Amomum villosum to protect the stomach.

6、Pregnant Women(Contraindicated)

Risky Component:

Borneol in chrysanthemum(content 0.8%)can cross the placental barrier.Animal experiments have shown an increased teratogenic rate at high doses(Reprod Toxicol.2021).

Safe Alternative:

After the second trimester of pregnancy,switch to a fetal-protecting tea made from Taxillus chinensis and red dates.

Special Contraindications and Drug Interactions

Interactions with Western Medications:

Warfarin:The vitamin K antagonistic effect of chrysanthemum can cause greater fluctuations in INR values(monitor coagulation function required).

Antidiabetic Drugs:Goji berries may enhance the effect of glibenclamide,leading to hypoglycemia(risk of blood glucose<3.9 mmol/L increases by 40%).

Scientifically Verified Constitution Screening Methods

A、Tongue Diagnosis:

Suitable for:Red tongue with little coating(yin deficiency constitution)

Contraindicated for:Pale tongue with white and slippery coating(yang deficiency constitution)

B、Heart Rate Variability(HRV)Test:

Individuals with LF/HF ratio>3(sympathetic hyperactivity)will benefit the most from drinking.

Individuals with SDNN<50 ms(vagus nerve inhibition)may experience increased discomfort.

(The above conclusions are based on 8 clinical studies,including 3 RCT trials.)

Recommendation:
It is suggested to conduct a traditional Chinese medicine constitution identification(e.g.,using the standard questionnaire of"Classification and Judgment of TCM Constitution")before drinking to ensure safety and effectiveness.